EGFR and lung carcinoma: The following cell lines were used for this analysis: A549 (KRASmut, p53wt), HCC827 (EGFRmut, p53mut), and NCI-H358 (KRASmut, p53null) in order to compare the activity of RESV and PRI-2191 on cells representing two main molecular subtype of lung cancer: EGFR mutant and KRAS mutant.