Among five pro-inflammatory and HF biomarkers, EAT showed positive linear associations with hs-CRP (r = 0.26), BNP (r = 21), gelactin-3 (r = 0.26), PIIINP (r = 0.37), and A-FABP (r = 0.41) (all p< 0.001). The gene discussed is NPPB; the disease is hydrops fetalis.