We evaluated the nuclear location of the chromosomal region surrounding MNX1 in the leukemia K562 cell line by FISH, and assessed the transcriptional activity of genes mapping in same region (i.e., LMBR1, NOM1, MNX1, UBE3C, and PTPRN2) by qRT-PCR. This evidence concerns the gene MNX1 and leukemia.