The other six variants found in our nine ChAc patients are apparently novel, and three of them are not even found in the Genome Aggregation Database (gnomad.broadinstitute.org/, last accessed on 30 December 2020) [36]; this unexpected high genetic variability suggests that many undetected VPS13A variants are actually present in the Italian and possibly other European populations. The gene discussed is VPS13A; the disease is Choreoacanthocytosis.