An abdominal window chamber was implanted onto the spontaneous murine pancreatic ductal adenocarcinoma (PDAC) model, LSL-KrasG12D/+;LSL-p53T172H/+;Pdx1-Cre (KPC), which was bred with ROSA26-pGAGGs-LSL-luciferase animals, resulting in a spontaneous bioluminescent PDAC animal model (KPC-Luc). This evidence concerns the gene PDX1 and pancreatic ductal adenocarcinoma.