NFKB1 and neoplasm: For example, following the photomarking of larger areas of B16F10 NF-κB-FLuc Dendra2 tumors, quantification of bioluminescence demonstrated no significant change in total tumor NF-κB transcriptional activation over time (Figure 5d and Figure S3c) or bioluminescence in photoswitched areas of the tumor (Figure 5e and Figure S3d).