BRAF and colorectal carcinoma: Yang et al. reported an association between the CT texture signatures and the predicted KRAS/NRAS/BRAF mutations status of CRC when using a support vector machine model yielded an area under curve (AUC) of 0.869 (95% CI, 0.780–0.958) in the primary cohort and 0.829 (95% CI, 0.718–0.939) in the validation cohort [84].