By exploiting the web-based tool Gene Expression Profiling Interactive Analysis, or GEPIA (http://gepia.cancer-pku.cn, access date 28 January 2021), to analyze RNA sequencing data from TCGA and GTEx projects, a significant increase in TENM1 expression has been found in thyroid carcinoma and in kidney renal clear cell carcinoma datasets compared to paired normal samples. The gene discussed is TENM1; the disease is thyroid gland carcinoma.