The impact of STAT3 on lymphomagenesis in Eμ-myc mice was evaluated by comparison of tumor development in STAT3wt/wt;Eμ-myc, STAT3fl/fl;tdT;Eμ-myc, and STAT3fl/fl;tdT;CD19Cre;Eμ-myc mice [Fig 3C]. The gene discussed is STAT3; the disease is neoplasm.