Many factors can be considered as the mechanismsinvolved in these kinds of memory impairments;however, one probable reason for these comorbiditiesmay be the chronic activation of inflammatory agents.Some investigators showed that the increase in cytokinesand increment of their signaling resulted in memoryimpairment, and there are many reports about the roleof inflammatory cytokines, such as IL-6 and TNF-αin the molecular mechanisms underlying learning andmemory consolidation (39). This evidence concerns the gene IL6 and memory impairment.