PTGS2 and non-small cell lung carcinoma: Silybin can target multiple cytokine‐induced signaling pathways, downregulate the expression of iNOS in NSCLC cells,256 and regulate the expression of iNOS and cyclooxygenase 2(COX2) in lung epithelial LM2 cells of tumorigenic mice by regulating the signals mediated by TNF‐α and interferon‐γ.257