Furthermore, it is reported that fucosterol has antiproliferative effects on human lung cancer cells by inducing apoptosis, cell cycle arrest and targeting of Raf/MEK/ERK signaling pathway, such as A549 and SK-LU-1 cancer cells, in addition, fucosterol could also inhibit the growth of xenografted tumours in mice44. Here, MAP2K7 is linked to lung carcinoma.