NISCH and ovarian cancer: Eventually, two H-2Kb epitopes with an affinity for MHC-I molecules lower than 500 nM and a predicted immunogenicity score above 0.1 were shown to be enriched in at least two out of three IP2-treated samples, the SGYEFIHKL 9mer from the tyrosine–tRNA ligase (UniProtKB - E9PX65) and the TNQDFIQRL 9mer (TL9) from the nischarin (UniProtKB–B7ZN33), which has been described as a tumor suppressor in breast and ovarian cancer (Fig. 5c)37.