We selected eight protein-coding DEGs from the RNA-Seq study for validation in the full cohort of 26 AD cases and 22 controls: SST, SLC7A2, TREM2, CXCR4 and MS4A6A and PARVG, INSR and IGF1R. As for the RNA-Seq cohort there was no difference in neuronal density between cases and controls for either region. This evidence concerns the gene TREM2 and Alzheimer disease.