In the AD-VIC, IGF1R (r2 = 0.35, p = 0.002), SST (r2 = 0.21, p = 0.02) expression was correlated with tau-positive neurons; PARVG (r2 = 0.25, p = 0.02) were correlated with residual neurons and CXCR4 (r2 = 0.28, p = 0.007) was correlated with Aβ areal fraction. This evidence concerns the gene CXCR4 and Alzheimer disease.