SST was significantly lower in the AD-PREC (p < 0.0001) while TREM2 (p < 0.0001), MS4A6A (p = 0.0004) and CXCR4 (p = 0.003) were higher in AD cases consistent with the RNA-Seq results (Fig. 4). The gene discussed is CXCR4; the disease is Alzheimer disease.