Furthermore, RNA IP revealed significant TINCR enrichment by STAU1 antibody compared with the IgG control (Fig. 5C).We also found that after using siRNA-STAU1 to knock down the STAU1 level in breast cancer cells, there was no significant change in the expression level of TINCR (Fig. 5D), and there was no significant change in the RNA/protein level of STAU1 in TINCR knockdown/overexpression cells (Fig. 5E, F), indicating that TINCR can directly bind with STAU1 without influencing its expression level. This evidence concerns the gene STAU1 and breast carcinoma.