MARK2 and leishmaniasis: One other intriguing finding that emerged from our analysis was that parasites from inflammatory volunteers express higher levels of Pfck1 – a serine-threonine kinase (Cheong and Virshup, 2011; Jiang et al., 2018) that has been shown to regulate pathogen virulence in leishmaniasis (Dan-Goor et al., 2013) and toxoplasmosis (Wang et al., 2016), and which may be able to directly regulate type I interferon signalling (Liu et al., 2009).