For example, CFIm25 causes 3′UTR shortening of a number of genes in glioblastoma cells and promotes tumor suppression [22]; however, CSTF2 in urothelial carcinoma of the bladder elicits 3′UTR shortening of RAC1 and contributes to UCB pathogenesis [23]. Here, NUDT21 is linked to bladder transitional cell carcinoma.