AKT1 and posterior cortical atrophy: The major finding of our work is that MBNL1-AS1 significantly downregulates in PCa tissues and cells, and MBNL1-AS1 inhibits the proliferation, invasion, and migration of PCa cells by sponging miR-181a-5p and regulating PTEN/PI3K/AKT/mTOR signaling pathway.