It was found that BRD4 was involved in pulmonary fibrosis by downregulating signals after growth factor stimulation [19], driving TGF-β-induced NOX4 expression in human lung fibroblasts [20], and mediating NF-kappaB-dependent epithelial-mesenchymal transition of airway epithelium [21]. Here, BRD4 is linked to pulmonary fibrosis.