In contrast, the gene expression of CD36, fatty acid translocase, and PGC-1α, a mitochondrial biogenesis marker, significantly decreased in the HF-fed ILKlox/loxAdCre mice compared with the HF-fed ILKlox/lox mice, while the UCP-1 expression was not altered (Figure 6G). The gene discussed is PPARGC1A; the disease is hydrops fetalis.