Although the gene expression of IL-10 significantly increased in the HF-fed ILKlox/loxAdCre mice compared with the HF-fed ILKlox/lox mice, genetic deletion of ILK in adipocytes did not affect the gene expression of the inflammatory markers including TNF-α, IL-6, or IL-1b (Figure 6E). The gene discussed is TNF; the disease is hydrops fetalis.