Any family history of breast cancer was associated with both P/LP BRCA1 variant (OR, 4.87; 95% CI, 2.82-8.42; P < .001) or a P/LP BRCA2 variant (OR, 3.07; 95% CI, 1.40-6.71; P = .005). Here, BRCA1 is linked to breast carcinoma.