PTH has been reported to inhibit cartilage degradation, terminal differentiation, and apoptosis of chondrocytes and to promote regeneration of articular cartilage in osteoarthritis (Sampson et al., 2011; Orth et al., 2013; Bellido et al., 2011; Yan et al., 2014; Chang et al., 2009; Lugo et al., 2012; Chen et al., 2018; Petersson et al., 2006). The gene discussed is PTH; the disease is osteoarthritis.