These include the mechanistic basis of the association between IL4i1 and different cancers (Carbonnelle-Puscian et al., 2009; Cousin et al., 2015; Sadik et al., 2020), the mode of action of LAAOs in snake venoms, and how this compares to mammalian IL4i1, the cell types that express IL4i1 and relative role of IL4i1-mediated microenvironmental amino acid depletion versus product generation. The gene discussed is IL4I1; the disease is cancer.