To explore more fully the potential functional mechanisms of OBI1, we investigated the 11 key proteins which interacted with OBI1 gene in the STRING Interaction Network (https://version11.string‐db.org/) (Figure 2) and found two of them associated with the degradation of myelin debris, the generation of new oligodendrocytes (MYD88),56 immune responses in CNS, and demyelinating disease activity (TOB1).57 This evidence concerns the gene TOB1 and demyelinating disease.