Meis1 (Myeloid ecotropic viral integration site 1) promotes glycolysis in hematopoietic stem cells, is upregulated in various cancers, and is naturally downregulated in the neonatal heart as CMs exit the cell cycle; fetal Meis1 suppression pushes fetal CMs from glycolysis to oxidative phosphorylation prematurely (Lindgren et al. 2019). Here, MEIS1 is linked to cancer.