Further statistical analysis, revealed that serum leptin levels above the cut-off value were associated with tumor ulceration (p = 0.0005, Figure 3C; or p = 0.0009, if no outliers were considered) and shorter DFS (117 vs. 314 days, p = 0.0217, Figure 3D; or p = 0.0245, if the outliers were removed). This evidence concerns the gene LEP and neoplasm.