IL-5 - Increasing serum level of IL-5 is observed in SLE patients (88) -Absence of significant differences between patients with SLE-LN and SLE without LN (88). - Low level of IL-5 is observed in SLE patients and without significant difference between SLE patients and controls (89) - Overexpression of IL-5 is observed in SLE patients with skin lesions (90). The gene discussed is IL5; the disease is systemic lupus erythematosus.