HLA-DRB1 and systemic lupus erythematosus: Another study by Mohd-Yusuf et al. (32) documented that the HLA-DRB1*0701 allele could be a risk allele for SLE development, while HLA-DRB1*1201, HLA-DRB1*1202, HLA-DRB1*1203, and HLA-DRB1*1301-22 alleles might confer protection in Malay SLE patients, evident by the significant reduction in the allele frequencies of DRB1*1301-22 after Bonferroni correction (32).