As shown in Figure 6A, pretreatment of exosomes derived from RPS3-overexpressing SGC7901R cells reduced the inhibitory effect of cisplatin on the tumor growth in compared with cisplatin (0.6 mg/kg) alone, while the pretreatment of exosomes derived from RPS3-silencing SGC7901R cells did the opposite effect (Figure 6A). The gene discussed is RPS3; the disease is neoplasm.