TRPA1 and Anxiety: Trpa1 KO mice displayed decreased anxiety-like behaviors in elevated-plus maze, better performance in the fear conditioning and novel location recognition tests, and enhanced social recognition behavior (Lee et al., 2017) (Table 2), possibly due, at least in part, to the evidence that TRPA1 negatively regulates hippocampal functions potentially through the suppression of neurite outgrowth (Lee et al., 2017).