A previous study demonstrated that SALL4 could bind to the promoter of CTNNB1 (the gene name of β-catenin) and further activate Wnt/β-catenin signaling in cervical cancer cells, and then we explored whether the transcriptional regulator SALL4 could regulate the expression of TRIB3. Using MEME-Chip, we screen the putative SALL4 binding motif: TTGTTTA(T)T(G)T that is found in the promoter region of TRIB3. Together, activation of the Wnt pathway and SALL4-related genes may result in poor survival in GC, giving new ideas for the follow-up study. The gene discussed is CTNNB1; the disease is cervical cancer.