Univariate Cox regression analysis revealed that the TNM stage, Lauren type, degree of differentiation, SALL4 expression, lymph node metastasis, vascular invasion, perineural invasion, location, sex, and distant metastasis were the significant prognostic indicators of GC (P < 0.05, respectively) (Table 2). The gene discussed is SALL4; the disease is metastatic malignant neoplasm in the lymph nodes.