By using univariate and multivariate Cox proportional hazard regression (41), it proved that CXCL7 in serum was an independent prognostic factor with worse outcomes compared with low concentration of CXCL7 in OCRC patients, and this result was consistent with previous studies that the overexpression of CXCL7 was a predicted signal of poor prognosis in CRC patients (42). Here, PPBP is linked to colorectal carcinoma.