SH3KBP1 and central nervous system cancer: Glioma CpG island methylator phenotype (G-CIMP) is another widely accepted prognosis marker of gliomas and glioma patients with NON G-CIMP always predict poor prognosis, thus we compared the expression levels of SH3KBP1 in G-CIMP and NON G-CIMP group and found that SH3KBP1 was highly expressed in NON G-CIMP group (Figure 1I).