Consistent with in vitro cell assays, in mice, tumors formed by PRKD3‐KO TNBC cells show significantly reduced tumor volumes and weights compared to those formed by parental cells, and either ectopic (over)expression of CLU or PRKD3 in PRKD3‐KO TNBC cells can restore TNBC tumor growth (Figure 5E–J). This evidence concerns the gene PRKD3 and neoplasm.