TWIST1 and cancer: For examples, CLU facilitates stress‐induced lipidation of LC3 and autophagosome biogenesis pathway to enhance cancer cell survival,[6] regulates Twist1 to mediate TGF‐β pathway to induce epithelial mesenchymal transition and metastasis,[40] and inhibits a constitutive activation of Cdc25C via the phosphatase PP2A to regulate Wee1–Cdk1 pathway to promote survival in cancer cells.[10] However, regulators of CLU in pathogenesis of TNBC are largely unknown.