On the other side, human breast‐cancer cell line MDA‐MB‐231 cultured in RADA16 platforms displayed a less malignant phenotype than when cultured in Col I or Matrigel.[268] In addition, noncancer cells (MCF10A) are able to form normal epithelial acini or tumor‐like spheroids in RADA16 hydrogels laminin‐supplemented depending on the stiffness of the matrix.[269] These findings suggest that the suitability of the TME created by RADA16 gels can differ for different cell types. The gene discussed is LAMB2; the disease is neoplasm.