OBI1 and hepatocellular carcinoma: Consistent with elevated mRNA level of LGALS3 in HCCLM3‐BM4 and RNF219‐transduced HCC cells (Figure S3B,C, Supporting Information), the secreted LGALS3 protein levels were also significantly increased in HCCLM3‐BM4 and RNF219‐overexpressed cells but decreased in RNF219‐silenced cells (Figure 2C and Figure S3D,E, Supporting Information).