OBI1 and hepatocellular carcinoma: Consistent with the biological function of each trans‐regulatory complex, the relative 5hmc/5mc ratio and levels of H4R3me2a and H3K4me3 on LGALS3 promoter were increased in RNF219‐upregulated and α‐catenin‐silenced HCC cells but decreased in RNF219‐silenced and α‐catenin‐transduced cells (Figure 6F,G).