The beneficial effects of quercetin on obesity was demonstrated through down-regulation of C/EBPβ (CCAAT/enhancer-binding protein beta), PPAR-γ, C/EBPα, and FABP4 as adipogenesis-related factors and TG synthetic enzymes such as lipin1, DGAT1 (diacylglycerol acyltransferase 1), and LPAATθ (lysophosphatidic acid acyltransferase). Here, CEBPB is linked to obesity due to melanocortin 4 receptor deficiency.