CBLN1 and chronic kidney disease: Notably, we also identified significantly elevated ceramide species (e.g., Cer d18:1/18:0, Cer d18:1/24:1) in basolateral inflammatory sEV that have been recently reported as increased in the circulation (plasma) of patients with chronic kidney disease (Mantovani et al., 2020) and may be of diagnostic utility in future validation studies.