Indeed, SNHL-causing mutations identified in North African countries currently involve only a small set of genes, i.e., GJB2, MYO7A, MYO15A, SLC26A4, TMC1, TMPRSS3, DFNB31, ESRRB, ESPN, DFNB59, LRTOMT, LHFPL5, PNPT1, TPRN, and MT-RNR1 (Chakchouk et al., 2015). This evidence concerns the gene ESRRB and sensorineural hearing loss disorder.