The gene FLRT2 is believed to have a role in tumor suppression in breast and prostate cancers (Wu et al., 2016; Bae et al., 2017), and in mouse models, FLRT2 has been found as a guiding agent in neuronal and vascular cells (Yamagishi et al., 2011; Seiradake et al., 2014). Here, FLRT2 is linked to prostate cancer.