CD4 and HIV infectious disease: We found similar expression patterns for these proteins, including pAKT (Figures 4A–C) and pATM (Figures 4D–F), which were inhibited in total CD4 T cells (Figures 4B, E), especially in p24- bystander cells, but were upregulated in p24+ cells at the initial phase (day 3) of HIV infection, and then gradually decreased with progressive HIV infection (Figures 4C, F).