STING activation also plays a crucial role in bronchopulmonary dysplasia (BPD) in preterm infants (a lung inflammatory conditions induced due to hyperoxia) due to an increase in the long-non coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) that interacts with the cAMP response element-binding protein (CREB) to increase its transcription (128). This evidence concerns the gene CREB1 and bronchopulmonary dysplasia.