C3 and glomerulosclerosis: These deposits did not consistently colocalize with immunoglobulins or other complement factors (19, 27, 44, 54, 67, 70, 72, 73, 75, 94–97, 103, 118, 127, 134, 139, 141, 175, 200), although C5b-9 and C3 colocalized more often in areas of glomerulosclerosis when immune deposits were present in other areas of the glomerulus (44, 67, 143) and both C5b-9 and C3 were more prominent in tubules and arteries in areas of tubulointerstitial injury (44, 57, 67, 75, 94, 96, 135, 139, 143, 200).