Correspondingly, glomerular staining of C5b-9 was more frequent, diffuse, and intense than in healthy kidneys and kidney diseases without immune deposits (44, 67, 75, 96, 126, 143), was found along the capillary wall in membranous nephropathy and lupus nephritis class V, in the mesangium in IgA nephropathy and lupus nephritis classes III and IV, and throughout the glomerulus in C3 glomerulopathy, thrombotic microangiopathies, and vasculitis. This evidence concerns the gene C5 and complement 3 glomerulopathy.