The evaluation of thrombophilia showed increased levels of fibrinogen (4.11 g/L, normal range 2.0–4.0 g/L), D-dimer (1.4 μg/ml, normal range 2.0–4.0 g/L), AT-III (134%, normal range 80.0–120.0%), and protein C (181%, normal range 65.0–140.0%). The gene discussed is SERPINC1; the disease is Rare hereditary thrombophilia.