CC-930 treatment also reduced leukocyte infiltration and the expression of inflammatory cytokines in AA-induced acute kidney injury – a finding consistent with the suppression of inflammation seen with JNK inhibition in the IRI and cisplatin models of acute kidney injury (Francescato et al., 2007; Wang et al., 2007; Kanellis et al., 2010). The gene discussed is MAPK8; the disease is acute kidney injury.