TNFSF10 and cancer: Regarding pathways related to biological functions, the integrin family cell surface interaction, homeostatic pathway and TNF-related apoptosis-inducing ligand/Apo-2L (TRAIL) signaling pathway were the most enriched pathways for CM-T3, CM-T2 and CM-BPH, respectively, which means that in the case of cancer cells, overexpression of these biological pathways is related to cell adhesion, migration and invasiveness (Sacca et al., 2019).