PARK7 and cancer: In a cell line from the epithelium of a hyperplasic prostate, BPH-1 cells, which express low abundance of the protein DJ-1 (a protein involved in transcriptional regulation, antioxidative stress reaction and chaperone) in comparison with cancer cells (LNCaP, Du145, PC-3), the addition of increasing concentrations of TRAIL correlated with an increased the expression of DJ-1.