The most commonly utilized cancer cell lines were human acute lymphoblastic leukemia (ALL cells), human acute myeloid leukemia cells (AML cells), PC3 cells (Prostate cancer cells), Hep G2 cells (Liver cancer cells), HCT116 (Colorectal cancer cells), MCF7 (Breast cancer cells), HT-29 and HCT 116 (human colon COX-2 positive and negative cells respectively), A549, SW2 cells, and human lung cancer cell line (H1299). Here, PTGS2 is linked to acute lymphoblastic leukemia.