The IL-1β values in the hippocampus revealed a significant main effect of sepsis [F(1, 16) = 171.4, P < 0.001], significant main effect of the mouse species (F(1, 16) = 38.7, P < 0.001), and significant interaction [F(1, 16) = 19.3, P < 0.001]. This evidence concerns the gene IL1B and Sepsis.