The above-mentioned class of cytokines and chemokines, such as CCL2 or CCL5, as well as ROS, are neuroinflammatory molecules putting a further burden onto neurons already damaged by various neurodegenerative illnesses such as Alzheimer’s disease (AD; Illes et al., 2019b), Parkinson’s disease (PD; Carmo et al., 2014), amyotrophic lateral sclerosis (Apolloni et al., 2014), and multiple sclerosis (MS; Domercq and Matute, 2019). This evidence concerns the gene CCL2 and Alzheimer disease.