To further investigate the clinical significance of CD14+HLA-DRlo/neg MDSCs in COVID-19, we performed an evaluation of 15 COVID-19 patients (7 ICU patients and 8 non-ICU patients) before and 1 day after negative SARS-CoV-2 nucleic acid results, and in 7 patients (5 ICU patients and 2 non-ICU patients) before, 1 day after, and 4-10 days after testing negative for the virus. Here, CD14 is linked to COVID-19.