CCL2 and age-related macular degeneration: Aqueous humor concentrations of CCL2, which is expressed by subretinal mononuclear phagocytes in AMD (Grossniklaus et al., 2002; Sennlaub et al., 2013) and implicated in inflammatory monocyte recruitment, is reduced following two months of anti-VEGF therapy (Motohashi et al., 2017).