Pericytes associated with angiogenic sprouts also express transmembrane and soluble VEGFR1, and the genetic ablation or the biochemical inhibition of PlGF or VEGFR1 in tumor models have implicated a direct role of VEGFR1 signaling in pericyte recruitment and vessel stabilization (Cicatiello et al., 2015; Tarallo et al., 2010). Here, PGF is linked to neoplasm.