RB1 and laryngeal carcinoma: Hs_miR-106b_3p is another miRNA that targets the 3’UTR of retinoblastoma (RB) gene [17] and upregulation of RB largely inhibited by miR-106b which further results in the induction of laryngeal carcinoma cells proliferation by deceased control of RB on G1/S transition of the cell cycle [17].